Each subject was evaluated for inclusion and exclusion criteria, and included in the study only if they met the appropriate criteria.PMCID: PMC3761532 PMID: 24149590 Effect of BETA 1, 31, 6 GLUCAN on Upper Respiratory Tract Infection Symptoms and Mood State in Marathon Athletes Shawn Talbott and Julie Talbott Author information Article notes Copyright and License information Disclaimer SupplementWatch GLH Nutrition, LLC, Draper, UT, USA.SupplementWatch GLH Nutrition, LLC, 648 Rocky Knoll, Draper, UT 84020, USA Received 2009 Apr 2; Accepted 2009 Jul 14.Copyright Journal of Sports Science and Medicine This article has been cited by other articles in PMC.
Abstract This was a placebo-controlled, double-blind study designed to evaluate the effect of a commercially available dietary supplement on upper-respiratory tract symptoms (URTI) and mood state. Subjects filled out the profile of mood state (POMS) assessment and a questionnaire style health log measuring health status and URTI symptoms after 2- and 4-week treatment administrations. During the course of the 4-week study, subjects in the treatment groups (250 mg and 500 mg BETA-GLUCAN per day) reported significantly fewer URTI symptoms, better overall health and decreased confusion, fatigue, tension, and anger, and increased vigor based on the POMS survey compared to placebo. BETA-GLUCAN may prevent URTI symptoms, and improve overall health and mood following a competitive marathon. Key points Beta-Glucan supplementation maintains immune function in endurance athletes. Beta-Glucan supplementation reduces post-exercise URTIs in marathon runners. Maintenance of post-exercise immune function is associated with improved mood state, including reduced fatigue and increased vigor in athletes. ![]() Exercise stress is similar to other stressors, such as psychological stress, which can lead to a weakened immune system and increased susceptibility to URTI and other disease states (Mackinnon, 1997 ). Psychological stress can also result from prolonged training and competition at the elite level. Elite athletes have deterioration in mood state during intense training periods, and before and after a marathon race (Achten et al., 2004; Hassmen and Blomstrand, 1991 ). Echowell Beta 1 Series Of SubjectThe current study employed a series of subject self-assessment questionnaires that addressed overall health status and URTI symptoms. In addition to evaluation of subjects for physical health, a psychological assessment known as the Profile of Mood States (POMS) was conducted to assess mood state. ![]() Methods Subjects This study was done in accordance with the Helsinki Declaration, as revised in 1983, for clinical research involving humans. Subjects signed informed consent documents after the study details were explained. Seventy-five healthy men (n 35) and women (n 40) ranging in age from 18-53 years (mean age: 36 9) participated in this study. Echowell Beta 1 Registration Area ForEnrollment took place through a recruitment table in the runner registration area for the Carlsbad Marathon (Carlsbad, California, USA) on January 20, 2007. Inclusion criteria included healthy, asymptomatic adults who were marathon participants, and a completed informed consent form. Exclusion criteria included those with current URTI symptoms, injury, and inability to complete all questionnaires and current use of antibiotics or other immune support products. Dietary supplement A placebo-controlled, double-blind design was employed for this study.
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